How does the shape and 3D folding of a protein relate to its biological function?
Tap here to reveal answer
Answer
The sequence of amino acids dictates how the protein chain folds into a precise three-dimensional shape. This 3D shape creates specific binding sites (e.g., the active site of an enzyme, binding sites of antibodies, and shape of receptors). If the shape alters (denaturation), the protein can no longer bind its substrate and loses its function.